Sunday, April 12, 2009

skeletal proteins in erythrocytes

SDS polyacrylamide gel electrophoresis differentiates
numerous membrane-associated erythrocyte
proteins. Each band of the gel is numbered,
and the individual proteins are assigned
to them. The main proteins include !- and "-
spectrin, ankyrin, an anion-channel protein
(band-3 protein), proteins 4.1 and 4.2, actin, and
others. The chromosomal localization of their
genes and associated diseases due to mutations
are known for man and mouse.

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