Sunday, April 12, 2009

!- and "-Spectrin

The main component of cytoskeletal proteins is
spectrin, a long protein composed of a 260 kDa
! chain and a 225 kDa " chain. The chains consist
of 20 (! chain) and 18 (" chain) subunits,
each with 106 amino acids. Each subunit is
composed of three !-helical protein strands
running counter to one another. Subunit 10 and
subunit 20 of the ! chain consist of five, instead
of three, parallel chains. The individual subunits
are assigned to different domains

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