Sunday, April 12, 2009

Clinical signs

DMD is the most distinctive progressive proximal
muscular dystrophy. The age of onset is
usually less than 3 years and signs are evident at
4–5 years; the patient requires awheelchair by
12 years and usually succumbs to the disorder
by age 20 years. Progressive muscularweakness
of the hips, thighs, and back cause difficulties in
walking and using steps. Lumbar lordosis and
enlarged but weak calves (pseudohypertrophy)
are visible (1). The affected child performs a
characteristic series of maneuvers to rise from a
kneeling position

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