Procollagen peptidases remove peptides at the
N-terminal and C-terminal ends to form tropocollagen
(5). Tropocollagen molecules are connected
by the numerous hydroxylated proline
and lysine residues to form collagen fibrils
(6). Each fibril consists of staggered, parallel
rows of end-to-end-tropocollagen molecules,
separated by gaps (7). Collagen fibrils are
visible as transverse stripes under the electron
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